The question is, who doesn't? I wouldn't have much to lose. I'm already know I'm insane, and I think it'd be kind of cool to experience the bleeding effect. to quote one of ~ZeKarmiSama's comics: "I can do the CSI glow-in-the-dark thing with just my eyeballs!" 8D
Of course, being me, I would think of all the ethical, moral and philosophical aspects of being in the Animus and the psychological and physical traumas it could inflict... and then I would think, fuck it, I'd jump in at the first chance. Abstergo, take me, take me now!